By Maria A. Ron, Trevor W. Robbins
Lately there were significant advances in components of scientific neuroscience together with neurogenetics, neuroimaging and the medical examine of cognizance. problems of mind and brain II brings jointly crucial findings because the prior quantity was once released in 1998. Imaging of the traditional and irregular brain figures prominently, and there's assurance of genes and behaviour, mind improvement, cognizance and aggression. New disease-oriented chapters element fresh advances in dementia, affective disease and drug use and abuse. medical chapters are paired with these describing neuropathology or experimental versions of illness.
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Extra resources for Disorders of Brain and Mind: Volume 2
Genetics of schizophrenia and the new millennium: progress and pitfalls. Am J Hum Genet, 68, 299–312. Bishop DVM, North T and Donlan C (1995). Genetic basis of speciﬁc language impairment: evidence from a twin study. Dev Med Child Neurol, 37, 56–71. Cardon LR and Bell J (2001). Association study designs for complex diseases. Nat Genet, 2, 91–9. Cardon LR, Smith SD, Fulker DW, Kimberling WJ, Pennington BF and DeFries JC (1994). Quantitative trait locus for reading disability on chromosome 6. Science, 266, 276–9.
Naturally occurring human genetic anomalies, in which candidate genes are either deleted or mutated, can be associated with quite speciﬁc neurocognitive consequences, which are reﬂected in symptom patterns. Such symptoms may in some cases be similar to those of idiopathic mental disorders such as autism or schizophrenia, although it should not be assumed that the genes in question necessarily play a role in predisposing to the idiopathic variants of those conditions. What can be stated, according to the framework outlined above, is that a genetic anomaly leading to a neurocognitive impairment can illuminate molecular and neurobiological processes which, when disrupted by any of a variety of means, can give rise to an equivalent biological or behavioural outcome.
123–35. Parkton, MD: York Press. 26 R Plomin DeFries JC and Fulker DW (1985). Multiple regression analysis of twin data. Behav Genet, 15, 467–73. DeFries JC and Fulker DW (1988). Multiple regression analysis of twin data: etiology of deviant scores versus individual differences. Acta Genet Med Gemellol, 37, 205–16. DeFries JC and Gillis JJ (1993). Genetics and reading disability. In Nature, Nurture and Psychology, ed. R Plomin and GE McClearn, pp. 121–45. Washington, DC: American Psychological Association.